PRMT2 Antibody - N-terminal region
Artikelnummer:
ASB-ARP40195_P050
- Bilder (3)
| Artikelname: | PRMT2 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP40195_P050 |
| Hersteller Artikelnummer: | ARP40195_P050 |
| Alternativnummer: | ASB-ARP40195_P050-25UL,ASB-ARP40195_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ChIP, WB |
| Spezies Reaktivität: | Human, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human PRMT2 |
| Alternative Synonym: | HRMT1L1 |
| The protein arginine methyltransferases (PRMTs) include a family of proteins with related putative methyltransferase domains that modify chromatin and regulate cellular transcription. PRMT2 inhibits NF-kappaB-dependent transcription and promotes apoptosis and it exerts this effect by blocking nuclear export of IkappaB-alpha through a leptomycin-sensitive pathway, increasing nuclear IkappaB-alpha and decreasing NF-kappaB DNA binding. PRMT2 also rendered cells susceptible to apoptosis by cytokines or cytotoxic drugs, likely due to its effects on NF-kappaB. |
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Quiescent human colon carcinoma HCT116 cultures were treated with 10% FBS for three time points (0, 15, 30min) or (0, 30, 60min) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site. |
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WB Suggested Anti-PRMT2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: 293T cell lysatePRMT2 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells |
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PRMT2 antibody - N-terminal region (ARP40195_P050) in Human HEK293T using Western Blot |
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