ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity.
WB Suggested Anti-ANP32A Antibody Titration: 1.25ug/ml Positive Control: Jurkat cell lysateANP32A is supported by BioGPS gene expression data to be expressed in Jurkat
ANP32A antibody - N-terminal region (ARP40204_T100) in Human Jurkat using Western Blot
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