NONO Antibody - N-terminal region
Artikelnummer:
ASB-ARP40715_T100
- Bilder (3)
| Artikelname: | NONO Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP40715_T100 |
| Hersteller Artikelnummer: | ARP40715_T100 |
| Alternativnummer: | ASB-ARP40715_T100-25UL,ASB-ARP40715_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IF, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human NONO |
| Alternative Synonym: | P54, NMT55, NRB54, MRXS34, P54NRB, PPP1R114 |
| NONO is DNA- and RNA binding protein, involved in several nuclear processes. It binds the conventional octamer sequence in double stranded DNA. It also binds single-stranded DNA and RNA at a site independent of the duplex site. It is involved in pre-mRNA splicing and interacts with U5 snRNA. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs, be involved in DNA unwinding by modulating the function of topoisomerase I/TOP1 and be involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination and may stabilize paired DNA ends. NONO binds to an enhancer element in long terminal repeats of endogenous intracisternal A particles (IAPs) and activates transcription. |
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Sample Type : subnuclear bodies-paraspeckles |
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WB Suggested Anti-NONO Antibody Titration: 1.25ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysate |
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NONO antibody - N-terminal region (ARP40715_T100) in Human HepG2 using Western Blot |
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