NXF3 Antibody - N-terminal region
Artikelnummer:
ASB-ARP40973_P050
- Bilder (3)
| Artikelname: | NXF3 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP40973_P050 |
| Hersteller Artikelnummer: | ARP40973_P050 |
| Alternativnummer: | ASB-ARP40973_P050-25UL,ASB-ARP40973_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human NXF3 |
| NXF3 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF3 has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. |
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WB Suggested Anti-NXF3 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cell lysate |
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Lanes: Lane 1: 7ug HeLa cystosolic lysate Lane 2: 7ug HeLa nuclear lysate Primary Antibody Dilution: 1:300 Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:500 Gene Name: NXF3 Submitted by: Seiji Masuda, Kitashirakawa Oiwakecho, Kyoto University |
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NXF3 antibody - N-terminal region (ARP40973_P050) in Human HepG2 using Western Blot |
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