UPF3B Antibody - N-terminal region
Artikelnummer:
ASB-ARP40998_T100
- Bilder (3)
| Artikelname: | UPF3B Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP40998_T100 |
| Hersteller Artikelnummer: | ARP40998_T100 |
| Alternativnummer: | ASB-ARP40998_T100-25UL,ASB-ARP40998_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Human, Mouse, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human UPF3B |
| Alternative Synonym: | MRX62, MRX82, UPF3X, HUPF3B, MRXS14, RENT3B, UPF3BP1, UPF3BP2, UPF3BP3, Upf3p-X |
| UPF3B is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The protein is one of two functional homologs to yeast Upf3p. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctionsThis gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene. |
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Rabbit Anti-UPF3B Antibody Catalog Number: ARP40998 Paraffin Embedded Tissue: Human Stomach Cellular Data: Epithelial cells of fundic gland Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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WB Suggested Anti-UPF3B Antibody Titration: 1.25ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysate |
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UPF3B antibody - N-terminal region (ARP40998_T100) in Human Jurkat using Western Blot |
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