MFN2 Antibody - N-terminal region

Artikelnummer: ASB-ARP42419_P050
Artikelname: MFN2 Antibody - N-terminal region
Artikelnummer: ASB-ARP42419_P050
Hersteller Artikelnummer: ARP42419_P050
Alternativnummer: ASB-ARP42419_P050-25UL,ASB-ARP42419_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MFN2
Alternative Synonym: HSG, MARF, CMT2A, CPRP1, CMT2A2, HMSN6A, CMT2A2A, CMT2A2B
MFN2 is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. It is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke.This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 86kDa
NCBI: 9927
UniProt: O95140
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-MFN2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Placenta
Host: Mouse
Target Name: MFN2
Sample Tissue: Mouse Testis
Antibody Dilution: 1ug/ml
Host: Rabbit
Target Name: MFN2
Sample Tissue: Human OVCAR-3 Whole Cell
Antibody Dilution: 0.5ug/ml
MFN2 antibody - N-terminal region (ARP42419_P050) in Human Placenta using Western Blot