RNF139 Antibody - N-terminal region
Artikelnummer:
ASB-ARP43092_P050
- Bilder (4)
| Artikelname: | RNF139 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP43092_P050 |
| Hersteller Artikelnummer: | ARP43092_P050 |
| Alternativnummer: | ASB-ARP43092_P050-25UL,ASB-ARP43092_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human RNF139 |
| Alternative Synonym: | RCA1, TRC8, HRCA1 |
| RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. The protein may be modified by phosphorylation. |
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WB Suggested Anti-RNF139 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: MCF7 cell lysateRNF139 is supported by BioGPS gene expression data to be expressed in MCF7 |
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Host: Rabbit Target: RNF139 Positive control (+): MCF7 Cell Lysate (N10) Negative control (-): HepG2 Cell Lysate (HG) Antibody concentration: 1ug/ml |
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RNF139 antibody - N-terminal region (ARP43092_P050) in Human MCF-7 using Western Blot |
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