Bovine, Canine, Equine, Human, Mouse, Porcine, Rat
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM45
Alternative Synonym:
RNF99
TRIM45 is a member of the tripartite motif family. It may function as a transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described. TRIM45 belongs to a family of tripartite motif (TRIM) proteins that play important roles in a variety of cellular functions, including cell proliferation, differentiation, development, oncogenesis, and apoptosis (Wang et al., 2004 [PubMed 15351693]).[supplied by OMIM].