Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat, Yeast, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Hdac4
Alternative Synonym:
HD4, 4932408F19Rik
Hdac4 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.