LDLR Antibody - C-terminal region
Artikelnummer:
ASB-ARP44305_P050
- Bilder (4)
| Artikelname: | LDLR Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP44305_P050 |
| Hersteller Artikelnummer: | ARP44305_P050 |
| Alternativnummer: | ASB-ARP44305_P050-25UL,ASB-ARP44305_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C-terminal region of Human LDLR |
| Alternative Synonym: | FH, FHC, FHCL1, LDLCQ2 |
| The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants. |
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Host: Rabbit Target Name: LDLR Sample Type: Fetal Heart lysates Antibody Dilution: 1.0ug/ml |
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25 ug of the indicated Human whole cell extracts was loaded onto a 6-18% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. The protein may be modified by glycosylation. |
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Host: Rabbit Target Name: LDLR Sample Tissue: Human Jurkat Whole Cell Antibody Dilution: 1ug/ml |
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LDLR Antibody - C-terminal region (ARP44305_P050) in Human Fetal Heart using Western Blot |
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