PTPN2 Antibody - N-terminal region
Artikelnummer:
ASB-ARP45362_T100
- Bilder (3)
| Artikelname: | PTPN2 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP45362_T100 |
| Hersteller Artikelnummer: | ARP45362_T100 |
| Alternativnummer: | ASB-ARP45362_T100-25UL,ASB-ARP45362_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human PTPN2 |
| Alternative Synonym: | PTN2, PTPT, TCPTP, TC-PTP, TCELLPTP |
| PTPN2 is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Three alternatively spliced variants of this gene, which encode isoforms differing at their extreme C-termini, have been described. The different C-termini are thought to determine the substrate specificity, as well as the cellular localization of the isoforms. Two highly related but distinctly processed pseudogenes that localize to distinct chromosomes have been reported. |
|
|
WB Suggested Anti-PTPN2 Antibody Titration: 2.5ug/ml Positive Control: Jurkat cell lysatePTPN2 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
|
|
Host: Rabbit Target Name: PTPN2 Sample Type: Jurkat Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 5.0ug/mL Peptide Concentration: 2.0ug/mL Lysate Quantity: 25ug/lane Gel Concentration: 12% |
|
|
PTPN2 antibody - N-terminal region (ARP45362_T100) in Human Jurkat using Western Blot |
Produktgarantie und fachkundiger Support
