STIM1 Antibody - middle region

Artikelnummer: ASB-ARP45434_P050
Artikelname: STIM1 Antibody - middle region
Artikelnummer: ASB-ARP45434_P050
Hersteller Artikelnummer: ARP45434_P050
Alternativnummer: ASB-ARP45434_P050-25UL,ASB-ARP45434_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human STIM1
Alternative Synonym: GOK, TAM, TAM1, IMD10, STRMK, D11S4896E
This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3 end of this gene situated 1.6 kb from the 5 end of the RRM1 gene.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 75kDa
NCBI: 6786
UniProt: Q13586
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-STIM1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: PANC1 cell lysateSTIM1 is supported by BioGPS gene expression data to be expressed in PANC1
RSMC cells
STIM1 antibody - middle region (ARP45434_P050) in Human PANC1 using Western Blot