HAVCR2 Antibody - N-terminal region
Artikelnummer:
ASB-ARP45550_P050
- Bilder (3)
| Artikelname: | HAVCR2 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP45550_P050 |
| Hersteller Artikelnummer: | ARP45550_P050 |
| Alternativnummer: | ASB-ARP45550_P050-25UL,ASB-ARP45550_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Canine, Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human HAVCR2 |
| Alternative Synonym: | TIM3, CD366, KIM-3, SPTCL, TIMD3, Tim-3, TIMD-3, HAVcr-2 |
| HAVCR2 regulates macrophage activation. HAVCR2 inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. HAVCR2 may be also involved in T-cell homing. HAVCR2 is the receptor for LGALS9.CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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WB Suggested Anti-HAVCR2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: OVCAR-3 cell lysate |
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Researcher: Dr. Maria de Lourdes Munoz, Department of Genetics and Molecular Biology Application: Western blotting Species + Tissue/Cell type: Aedes albopictus c6/36 cells, Aedes aegypti midguts, human WBC How many ugs of tissue/cell lysate run on the gel: 1. 10 ug Aedes albopictus c6/36 cell lysate 2. 10 ug Aedes aegypti midgut lysate 3. 10 ug human white blood cell lysate Primary antibody dilution: 1:1000 Secondary antibody: Goat Anti-Rabbit HRP Secondary antibody dilution: 1:5000 |
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HAVCR2 antibody - N-terminal region (ARP45550_P050) in Human OVCAR-3 using Western Blot |
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