The immunogen is a synthetic peptide directed towards the middle region of human CENPA
Alternative Synonym:
CenH3, CENP-A
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA is a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-CENPA Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Hela cell lysate.CENPA is strongly supported by BioGPS gene expression data to be expressed in HeLa
Host: Rabbit Target Name: CENPA Sample Type: 721_B Antibody Dilution: 1.0ug/mlCENPA is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
CENPA antibody - middle region (ARP46041_P050) in Human HeLa using Western Blot
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