RMI1 Antibody - N-terminal region
Artikelnummer:
ASB-ARP46340_P050
- Bilder (3)
| Artikelname: | RMI1 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP46340_P050 |
| Hersteller Artikelnummer: | ARP46340_P050 |
| Alternativnummer: | ASB-ARP46340_P050-25UL,ASB-ARP46340_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human RMI1 |
| Alternative Synonym: | BLAP75, FAAP75, C9orf76 |
| RMI1 is an essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. RMI1 promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. RMI1 is required for BLM phosphorylation during mitosis. Within the BLM complex, RMI1 is required for BLM and TOP3A stability.RMI1 is a component of protein complexes that limit DNA crossover formation via the dissolution of double Holliday junctions (Raynard et al., 2006 [PubMed 16595695]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-136 BP327553.1 1-136 137-885 DN997105.1 9-757 886-2740 AL732446.4 14777-16631 2741-3508 BC039999.2 2566-3333 |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. The protein may be modified by glycosylation and phosphorylation. |
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WB Suggested Anti-RMI1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Transfected 293T |
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RMI1 antibody - N-terminal region (ARP46340_P050) in Transfected 293T using Western Blot |
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