Fto Antibody - N-terminal region
Artikelnummer:
ASB-ARP47473_P050
- Bilder (3)
| Artikelname: | Fto Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP47473_P050 |
| Hersteller Artikelnummer: | ARP47473_P050 |
| Alternativnummer: | ASB-ARP47473_P050-25UL,ASB-ARP47473_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IP, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Sheep, Yeast |
| Immunogen: | The immunogen is a synthetic peptide corresponding to a region of Mouse |
| Alternative Synonym: | AW743446, mKIAA1752 |
| Fto is a dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Fto has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Fto has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Fto has no activity towards 1-methylguanine and no detectable activity towards double-stranded DNA. Fto requires molecular oxygen, alpha-ketoglutarate and iron. Fto contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Fto contributes to the regulation of body size and body fat accumulation. |
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FTO was immunoprecipitated from 2 mg HEK293 Whole Cell Lysate with ARP47473_P050 with 1:200 dilution. Western blot was performed using ARP47473_P050 at 1/1000 dilution. Lane 1: Control IP in HEK293 Whole Cell Lysate. Lane 2: FTO IP with ARP47473_P050 in HEK293 Whole Cell Lysate. Lane 3: Input of HEK293 Whole Cell Lysate. |
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WB Suggested Anti-Fto Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Mouse Brain |
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Fto antibody - N-terminal region (ARP47473_P050) in Mouse Brain using Western Blot |
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