PDHA1 Antibody - N-terminal region
Artikelnummer:
ASB-ARP48136_T100
- Bilder (3)
| Artikelname: | PDHA1 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP48136_T100 |
| Hersteller Artikelnummer: | ARP48136_T100 |
| Alternativnummer: | ASB-ARP48136_T100-25UL,ASB-ARP48136_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human PDHA1 |
| Alternative Synonym: | PDHA, PDHAD, PHE1A, PDHCE1A |
| The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1), dihydrolipoyl transacetylase (DLAT), and dihydrolipoyl dehydrogenase (DLD). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex.The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1), dihydrolipoyl transacetylase (DLAT, MIM 608770) (E2, EC 2.3.1.12), and dihydrolipoyl dehydrogenase (DLD, MIM 238331) (E3, EC 1.8.1.4). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex (Brown et al., 1994 [PubMed 7853374]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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WB Suggested Anti-PDHA1 Antibody Titration: 5.0ug/ml Positive Control: HepG2 cell lysatePDHA1 is supported by BioGPS gene expression data to be expressed in HepG2 |
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WB Suggested Anti-PDHA1 Antibody Positive Control: Lane 1: 80ug mouse brain extract Primary Antibody Dilution : 1:500 Secondary Antibody : IRDye 800 CW goat anti-rabbit from Li-COR Bioscience Secondry Antibody Dilution : 1:20,000 Submitted by: Dr. Yuzhi Chen, University of Arkansas for Medical Science |
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PDHA1 antibody - N-terminal region (ARP48136_T100) in Human HepG2 using Western Blot |
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