MAP4K2 Antibody - N-terminal region

Artikelnummer: ASB-ARP48631_P050
Artikelname: MAP4K2 Antibody - N-terminal region
Artikelnummer: ASB-ARP48631_P050
Hersteller Artikelnummer: ARP48631_P050
Alternativnummer: ASB-ARP48631_P050-25UL,ASB-ARP48631_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K2
Alternative Synonym: GCK, BL44, RAB8IP
MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 92 kDa
NCBI: 5871
UniProt: Q12851
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 0.5 ug/mL of the antibody was used in this experiment. The protein may be modified by phosphorylation.
WB Suggested Anti-MAP4K2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: HepG2 cell lysate
MAP4K2 antibody - N-terminal region (ARP48631_P050) in Human HepG2 using Western Blot