HLA-F Antibody - N-terminal region
Artikelnummer:
ASB-ARP49411_P050
- Bilder (3)
| Artikelname: | HLA-F Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP49411_P050 |
| Hersteller Artikelnummer: | ARP49411_P050 |
| Alternativnummer: | ASB-ARP49411_P050-25UL,ASB-ARP49411_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Human, Porcine |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human HLA-F |
| Alternative Synonym: | HLAF, CDA12, HLA-5.4, HLA-CDA12 |
| HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain. |
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Rabbit Anti-HLA-F Antibody Catalog Number: ARP49411_P050 Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue Observed Staining: Membrane and cytoplasmic in alveolar type I cells Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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WB Suggested Anti-HLA-F Antibody Titration: 0.2-1 ug/ml Positive Control: 721_B cell lysateHLA-F is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells |
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HLA-F antibody - N-terminal region (ARP49411_P050) in Human 721_B using Western Blot |
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