JPH3 Antibody - N-terminal region

Artikelnummer: ASB-ARP49534_P050
Artikelname: JPH3 Antibody - N-terminal region
Artikelnummer: ASB-ARP49534_P050
Hersteller Artikelnummer: ARP49534_P050
Alternativnummer: ASB-ARP49534_P050-25UL,ASB-ARP49534_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human JPH3
Alternative Synonym: JP3, HDL2, JP-3, TNRC22, CAGL237
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. JPH3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntingtons disease (HD)-like 2 locus have been identified in the gene that encodes JPH3 protein. Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntingtons disease (HD)-like 2 locus have been identified in this gene, which is a member of the junctophilin gene family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 81kDa
NCBI: 57338
UniProt: Q8WXH2
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-JPH3 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
WB Suggested Anti-JPH3 Antibody Titration: 1.0ug/ml
Positive Control: Human Brain cell lysate
JPH3 antibody - N-terminal region (ARP49534_P050) in Human HepG2 using Western Blot