The immunogen is a synthetic peptide directed towards the C terminal region of human NTRK2
Alternative Synonym:
OBHD, TRKB, DEE58, trk-B, EIEE58, GP145-TrkB
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders.