OAS1 Antibody - C-terminal region
Artikelnummer:
ASB-ARP51360_P050
- Bilder (3)
| Artikelname: | OAS1 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP51360_P050 |
| Hersteller Artikelnummer: | ARP51360_P050 |
| Alternativnummer: | ASB-ARP51360_P050-25UL,ASB-ARP51360_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human OAS1 |
| Alternative Synonym: | OIAS, IFI-4, OIASI, E18/E16 |
| OAS1 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2-specific nucleotidyl transfer reactions to synthesize 2,5-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Mutations in this gene have been associated with host susceptibility to viral infection.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2-specific nucleotidyl transfer reactions to synthesize 2,5-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. |
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Immunohistochemistry of formalin fixed, paraffin-embeddedhumanTonsil tissue. PrimaryAntibody concentration 5 ug/ml. |
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WB Suggested Anti-OAS1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human heart |
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OAS1 antibody - C-terminal region (ARP51360_P050) in Human heart using Western Blot |
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