FBXO32 Antibody - N-terminal region

Artikelnummer: ASB-ARP52865_P050
Artikelname: FBXO32 Antibody - N-terminal region
Artikelnummer: ASB-ARP52865_P050
Hersteller Artikelnummer: ARP52865_P050
Alternativnummer: ASB-ARP52865_P050-25UL,ASB-ARP52865_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO32
Alternative Synonym: Fbx32, MAFbx
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 42 kDa
NCBI: 114907
UniProt: Q0VAQ6
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment.
WB Suggested Anti-FBXO32 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate
FBXO32 antibody - N-terminal region (ARP52865_P050) in Human Jurkat using Western Blot