IMPDH2 Antibody - C-terminal region

Artikelnummer: ASB-ARP54366_P050
Artikelname: IMPDH2 Antibody - C-terminal region
Artikelnummer: ASB-ARP54366_P050
Hersteller Artikelnummer: ARP54366_P050
Alternativnummer: ASB-ARP54366_P050-25UL,ASB-ARP54366_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IMPDH2
Alternative Synonym: IMPD2, IMPDH-II
IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It catalyzes the NAD-dependent oxidation of inosine-5-monophosphate into xanthine-5-monophosphate, which is then converted into guanosine-5-monophosphate. IMPDH2 is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5-monophosphate into xanthine-5-monophosphate, which is then converted into guanosine-5-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 56kDa
NCBI: 3615
UniProt: P12268
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-IMPDH2 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
Host: Rabbit
Target: IMPDH2
Positive control (+): Human Liver (LI)
Negative control (-): 293T Cell Lysate (2T)
Antibody concentration: 0.5ug/ml
IMPDH2 antibody - C-terminal region (ARP54366_P050) in Human HepG2 using Western Blot