TBK1 Antibody - N-terminal region
Artikelnummer:
ASB-ARP54921_P050
- Bilder (2)
| Artikelname: | TBK1 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP54921_P050 |
| Hersteller Artikelnummer: | ARP54921_P050 |
| Alternativnummer: | ASB-ARP54921_P050-25UL,ASB-ARP54921_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human TBK1 |
| Alternative Synonym: | NAK, T2K, IIAE8, FTDALS4 |
| The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. TBK1 is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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WB Suggested Anti-TBK1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Hela cell lysate |
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TBK1 antibody - N-terminal region (ARP54921_P050) in Human HeLa using Western Blot |
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