SESN1 Antibody - middle region

Artikelnummer: ASB-ARP55059_P050
Artikelname: SESN1 Antibody - middle region
Artikelnummer: ASB-ARP55059_P050
Hersteller Artikelnummer: ARP55059_P050
Alternativnummer: ASB-ARP55059_P050-25UL,ASB-ARP55059_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SESN1
Alternative Synonym: PA26, SEST1
This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 64kDa
NCBI: 27244
UniProt: Q9Y6P5-2
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Host: Rabbit
Target Name: SESN1
Sample Type: THP-1 Whole cell lysates
Antibody Dilution: 1.0ug/ml
Host: Mouse
Target Name: SESN1
Sample Tissue: Mouse Spleen
Antibody Dilution: 1ug/ml
SESN1 Antibody - middle region (ARP55059_P050) in Human THP-1 using Western Blot