IL15 Antibody - N-terminal region
Artikelnummer:
ASB-ARP55616_P050
- Bilder (4)
| Artikelname: | IL15 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP55616_P050 |
| Hersteller Artikelnummer: | ARP55616_P050 |
| Alternativnummer: | ASB-ARP55616_P050-25UL,ASB-ARP55616_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human IL15 |
| Alternative Synonym: | IL-15 |
| IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each others activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each others activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. |
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WB Suggested Anti-IL15 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: 293T cell lysate |
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Host: Rabbit Target: IL15 Positive control (+): A549 Cell Lysate (N03) Negative control (-): U937 Cell Lysate (N31) Antibody concentration: 3ug/ml |
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Host: Rabbit Target Name: IL15 Sample Tissue: Human RPMI 8226 Whole Cell Antibody Dilution: 1ug/ml |
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IL15 antibody - N-terminal region (ARP55616_P050) in Human 293T using Western Blot |
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