RHOC Antibody - N-terminal region
Artikelnummer:
ASB-ARP55742_P050
- Bilder (4)
| Artikelname: | RHOC Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP55742_P050 |
| Hersteller Artikelnummer: | ARP55742_P050 |
| Alternativnummer: | ASB-ARP55742_P050-25UL,ASB-ARP55742_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Yeast, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human RHOC |
| Alternative Synonym: | H9, ARH9, ARHC, RHOH9 |
| RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of RHOC is associated with tumor cell proliferation and metastasis.This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
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Sample Type: Brugia malayi intestinal cross sectionPrimary Antibody Dilution: 1:200Secondary Antibody: Anti-rabbit-APSecondary Antibody Dilution: 1:5000Gene Name: RHOCSubmitted by: Peter U. Fischer, Ph.D., Research Associate Professor, Washington University School of Medicine, Infectious Disease Division, Campus Mailbox 8051, 660 S. Euclid Ave, St. Louis, MO 63110 USA, Tel 314-454-7876 Fax 314-454-5293 |
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WB Suggested Anti-RHOC Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human Liver |
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Lanes: Lane 1: 20ug of Brugia malayi total worm extract Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:5000 Gene Name: RHOC Submitted by: Peter U. Fischer, Washington University School of Medicine |
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RHOC antibody - N-terminal region (ARP55742_P050) in Human Liver using Western Blot |
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