SELENOP Antibody - N-terminal region
Artikelnummer:
ASB-ARP56299_P050
- Bilder (3)
| Artikelname: | SELENOP Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP56299_P050 |
| Hersteller Artikelnummer: | ARP56299_P050 |
| Alternativnummer: | ASB-ARP56299_P050-25UL,ASB-ARP56299_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Equine, Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human SEPP1 |
| Alternative Synonym: | SeP, SELP, SEPP, SEPP1 |
| This gene encodes a selenoprotein that is predominantly expressed in the liver and secreted into the plasma. This selenoprotein is unique in that it contains multiple selenocysteine (Sec) residues per polypeptide (10 in human), and accounts for most of the selenium in plasma. It has been implicated as an extracellular antioxidant, and in the transport of selenium to extra-hepatic tissues via apolipoprotein E receptor-2 (apoER2). Mice lacking this gene exhibit neurological dysfunction, suggesting its importance in normal brain function. Sec is encoded by the UGA codon, which normally signals translation termination. The 3 UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The mRNA for this selenoprotein contains two SECIS elements. Alternatively spliced transcript variants have been found for this gene. |
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WB Suggested Anti-SEPP1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: 293T cell lysateSEPP1 is supported by BioGPS gene expression data to be expressed in HEK293T |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. The protein may be modified by glycosylation. |
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SEPP1 antibody - N-terminal region (ARP56299_P050) in Human 293T using Western Blot |
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