PTPN11 Antibody - N-terminal region
Artikelnummer:
ASB-ARP56494_P050
- Bilder (3)
| Artikelname: | PTPN11 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP56494_P050 |
| Hersteller Artikelnummer: | ARP56494_P050 |
| Alternativnummer: | ASB-ARP56494_P050-25UL,ASB-ARP56494_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human PTPN11 |
| Alternative Synonym: | CFC, NS1, JMML, SHP2, BPTP3, PTP2C, METCDS, PTP-1D, SH-PTP2, SH-PTP3 |
| The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. |
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Immunohistochemistry with Lung tissue at an antibody concentration of 5ug/ml using anti-PTPN11 antibody (ARP56494_P050) |
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WB Suggested Anti-PTPN11 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: THP-1 cell lysate |
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PTPN11 antibody - N-terminal region (ARP56494_P050) in Human THP-1 using Western Blot |
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