PRKACA Antibody - N-terminal region

Artikelnummer: ASB-ARP57828_P050
Artikelname: PRKACA Antibody - N-terminal region
Artikelnummer: ASB-ARP57828_P050
Hersteller Artikelnummer: ARP57828_P050
Alternativnummer: ASB-ARP57828_P050-25UL,ASB-ARP57828_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRKACA
Alternative Synonym: CAFD1, PKACA, PPNAD4
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 40
NCBI: 5566
UniProt: A8K8B9
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-PRKACA Antibody
Catalog Number: ARP57828_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: N/A
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-PRKACA Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Muscle
PRKACA antibody - N-terminal region (ARP57828_P050) in Human Muscle using Western Blot