RB1 Antibody - N-terminal region
Artikelnummer:
ASB-ARP58065_P050
- Bilder (3)
| Artikelname: | RB1 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP58065_P050 |
| Hersteller Artikelnummer: | ARP58065_P050 |
| Alternativnummer: | ASB-ARP58065_P050-25UL,ASB-ARP58065_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Human, Mouse, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human RB1 |
| Alternative Synonym: | RB, pRb, OSRC, pp110, p105-Rb, PPP1R130, p110-RB1 |
| The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
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WB Suggested Anti-RB1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Jurkat cell lysateRB1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
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Researcher: Anke Rauch & Dr. Oliver Kramer, Institute for Biochemistry and Biophysics, Center for Molecular Biomedicine, Friedrich-Schiller University Jena Application: Western blotting Species+tissue/cell type: Human Colon carcinoma cell line HCT116 How many ugsof tissue/cell lysate run on the gel:1. 30 ug HCT116 lysate (No stress)2. 30 ug HCT116 lysate(low stress)3. 30 ug HCT116 lysate(high stress) Primary antibody dilution: 1:2000 Secondary antibody: Anti-rabbit HRP Secondary antibody dilution: 1:5000 |
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RB1 antibody - N-terminal region (ARP58065_P050) in Human Jurkat using Western Blot |
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