APRT Antibody - N-terminal region
Artikelnummer:
ASB-ARP58422_P050
- Bilder (3)
| Artikelname: | APRT Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP58422_P050 |
| Hersteller Artikelnummer: | ARP58422_P050 |
| Alternativnummer: | ASB-ARP58422_P050-25UL,ASB-ARP58422_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Guinea pig, Human, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human APRT |
| Alternative Synonym: | AMP, APRTD |
| Adenine phosphoribosyltransferase (APRT) belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. |



