This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sample Type: Human Cornea Dilution: 1:200
WB Suggested Anti-ALDH1A1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: ACHN cell lysateALDH1A1 is supported by BioGPS gene expression data to be expressed in ACHN
ALDH1A1 antibody - middle region (ARP58737_P050) in Human ACHN using Western Blot
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