TLR4 Antibody - C-terminal region
Artikelnummer:
ASB-ARP59160_P050
- Bilder (3)
| Artikelname: | TLR4 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP59160_P050 |
| Hersteller Artikelnummer: | ARP59160_P050 |
| Alternativnummer: | ASB-ARP59160_P050-25UL,ASB-ARP59160_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human TLR4 |
| Alternative Synonym: | TOLL, CD284, TLR-4, ARMD10 |
| The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Also, several transcript variants of this gene have been found, but the protein coding potential of most of them is uncertain. |
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WB Suggested Anti-TLR4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: A549 cell lysate |
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Lanes: Lane 1: Untreated human U251 cell lysate Lane 2: IL-1beta treated human U251 cell lysate Primary Antibody Dilution: 1:500 Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:500 Gene Name: TLR4 Submitted by: Anonymous |
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TLR4 antibody - C-terminal region (ARP59160_P050) in Human A549 using Western Blot |
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