Pcsk1n Antibody - N-terminal region
Artikelnummer:
ASB-ARP59210_P050
- Bilder (3)
| Artikelname: | Pcsk1n Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP59210_P050 |
| Hersteller Artikelnummer: | ARP59210_P050 |
| Alternativnummer: | ASB-ARP59210_P050-25UL,ASB-ARP59210_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Guinea pig, Human, Mouse, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Pcsk1n |
| Alternative Synonym: | Saas |
| Pcsk1n may function in the control of the neuroendocrine secretory pathway. It is proposed to be a specific endogenous inhibitor of PCSK1. ProSAAS and Big PEN-LEN, both containing the C-terminal inhibitory domain, but not the processed peptides reduce PCSK1 activity in the endoplasmic reticulum and Golgi. It reduces the activity of the 87 kDa form but not the autocatalytically derived 65 kDa form of PCSK1. Subsequent processing of proSAAS may eliminate the inhibition. Slows down convertase-mediated processing of proopiomelanocortin and proenkephalin. Pcsk1n may control the intracellular timing of PCSK1 rather than its total level of activity. The function of the processed secreted peptides is not known. |
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Host: Rabbit Target Name: Pcsk1n Sample Type: Rat Thymus lysates Antibody Dilution: 1.0ug/ml |
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Host: Rabbit Target Name: PCSK1N Sample Tissue: Rat Testis Antibody Dilution: 3ug/ml |
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Pcsk1n Antibody - N-terminal region (ARP59210_P050) in Rat Thymus using Western Blot |
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