F8 Antibody - C-terminal region

Artikelnummer: ASB-ARP60040_P050
Artikelname: F8 Antibody - C-terminal region
Artikelnummer: ASB-ARP60040_P050
Hersteller Artikelnummer: ARP60040_P050
Alternativnummer: ASB-ARP60040_P050-25UL,ASB-ARP60040_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Human, Rabbit, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human F8
Alternative Synonym: AHF, F8B, F8C, HEMA, FVIII, DXS1253E
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 79kDa
NCBI: 2157
UniProt: P00451
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-F8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 721_B cell lysate
Host: Rabbit
Target Name: F8
Sample Type: 721_B Whole Cell
Lane A: Primary Antibody
Lane B: Primary Antibody + Blocking Peptide
Primary Antibody Concentration: 1ug/ml
Peptide Concentration: 5ug/ml
Lysate Quantity: 25ug/lane
Gel Concentration: 0.12%
Host: Rabbit
Target Name: F8
Sample Tissue: Human Ovary Tumor
Antibody Dilution: 1ug/ml
F8 antibody - C-terminal region (ARP60040_P050) in Human 721_B using Western Blot