FGFR2 Antibody - C-terminal region

Artikelnummer: ASB-ARP60044_P050
Artikelname: FGFR2 Antibody - C-terminal region
Artikelnummer: ASB-ARP60044_P050
Hersteller Artikelnummer: ARP60044_P050
Alternativnummer: ASB-ARP60044_P050-25UL,ASB-ARP60044_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FGFR2
Alternative Synonym: BEK, JWS, BBDS, CEK3, CFD1, ECT1, KGFR, TK14, TK25, BFR-1, CD332, K-SAM
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 78kDa
NCBI: 2263
UniProt: P21802
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-FGFR2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Hela cell lysateFGFR2 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells
Sample Type: HEK293 (20ug)
Primary Dilution:1:200
Secondary Dilution:1:5000
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Host: Mouse
Target Name: FGFR2
Sample Tissue: Mouse Testis
Antibody Dilution: 1ug/ml
FGFR2 antibody - C-terminal region (ARP60044_P050) in Human HeLa using Western Blot