CTSC Antibody - N-terminal region
Artikelnummer:
ASB-ARP60117_P050
- Bilder (3)
| Artikelname: | CTSC Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP60117_P050 |
| Hersteller Artikelnummer: | ARP60117_P050 |
| Alternativnummer: | ASB-ARP60117_P050-25UL,ASB-ARP60117_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Human, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N-terminal region of Human CTSC |
| Alternative Synonym: | JP, HMS, JPD, PLS, CPPI, DPP1, DPPI, PALS, DPP-I, PDON1 |
| CTSC is a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in CTSC have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. |
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Rabbit Anti-CTSC Antibody Catalog Number: ARP60117_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic in lysosomes Primary Antibody Concentration: 1:100 Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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Host: Rabbit Target Name: CTSC Sample Type: HCT15 Whole Cell lysates Antibody Dilution: 1.0ug/ml |
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CTSC Antibody - N-terminal region (ARP60117_P050) in Human HCT15 using Western Blot |
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