DDB2 Antibody - C-terminal region

Artikelnummer: ASB-ARP60163_P050
Artikelname: DDB2 Antibody - C-terminal region
Artikelnummer: ASB-ARP60163_P050
Hersteller Artikelnummer: ARP60163_P050
Alternativnummer: ASB-ARP60163_P050-25UL,ASB-ARP60163_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DDB2
Alternative Synonym: XPE, DDBB, UV-DDB2
This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 48kDa
NCBI: 1643
UniProt: Q92466
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-DDB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Placenta
Host: Rabbit
Target Name: DDB2
Sample Type: Human Fetal Brain
Antibody Dilution: 1.0ug/ml
DDB2 antibody - C-terminal region (ARP60163_P050) in Human Placenta using Western Blot