The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sample Type: Human Hep-2 cellsPrimary Antibody Dilution: 1:500Secondary Antibody: Goat anti-rabbit-Alexa Fluor 568Secondary Antibody Dilution: 1:400Color/Signal Descriptions: Red: CTPS2 Blue: DAPIGene Name: CTPS2Submitted by: S. John Calise, Edward Chan Lab, University of Florida
WB Suggested Anti-CTPS2 Antibody Titration: 1.0 ug/ml Positive Control: Hela Whole CellCTPS2 is supported by BioGPS gene expression data to be expressed in HeLa
CTPS2 antibody - N-terminal region (ARP62443_P050) in Human HeLa using Western Blot
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