WASL Antibody - middle region

Artikelnummer: ASB-ARP63498_P050
Artikelname: WASL Antibody - middle region
Artikelnummer: ASB-ARP63498_P050
Hersteller Artikelnummer: ARP63498_P050
Alternativnummer: ASB-ARP63498_P050-25UL,ASB-ARP63498_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat
Alternative Synonym: NWASP, WASPB, N-WASP
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 56kDa
NCBI: 8976
UniProt: O00401
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-WASL Antibody
Catalog Number: ARP63498_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-WASL Antibody
Titration: 1.0 ug/ml
Positive Control: Fetal Lung
Host: Mouse
Target Name: WASL
Sample Tissue: Mouse Skeletal Muscle
Antibody Dilution: 1ug/ml
WASL antibody - middle region (ARP63498_P050) in Human Fetal Lung using Western Blot