KCNQ4 Antibody - C-terminal region
Artikelnummer:
ASB-ARP74603_P050
- Bilder (3)
| Artikelname: | KCNQ4 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP74603_P050 |
| Hersteller Artikelnummer: | ARP74603_P050 |
| Alternativnummer: | ASB-ARP74603_P050-25UL,ASB-ARP74603_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human KCNQ4 |
| Alternative Synonym: | DFNA2, KV7.4, DFNA2A |
| The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. |
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Host: Rabbit Target Name: KCNQ4 Sample Tissue: HepG2 Whole Cell lysates Antibody Dilution: 1ug/ml |
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Host: Mouse Target Name: KCNQ4 Sample Tissue: Mouse Brain Antibody Dilution: 1ug/ml |
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KCNQ4 Antibody - C-terminal region (ARP74603_P050) in Human HepG2 Whole Cell using Western Blot |
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