CARD11 Antibody - middle region

Artikelnummer: ASB-ARP78121_P050
Artikelname: CARD11 Antibody - middle region
Artikelnummer: ASB-ARP78121_P050
Hersteller Artikelnummer: ARP78121_P050
Alternativnummer: ASB-ARP78121_P050-25UL,ASB-ARP78121_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Human
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CARD11
Alternative Synonym: PPBL, BENTA, BIMP3, IMD11, CARMA1, IMD11A
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 128 kDa
NCBI: 84433
UniProt: Q8TES3
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Host: Rabbit
Target Name: CARD11
Sample Tissue: Human HeLa Whole Cell lysates
Antibody Dilution: 1ug/ml
Host: Mouse
Target Name: CARD11
Sample Tissue: Mouse Brain
Antibody Dilution: 1ug/ml
CARD11 Antibody - middle region (ARP78121_P050) in Human HeLa Whole Cell using Western Blot