XIAP Antibody - middle region
Artikelnummer:
ASB-ARP79020_P050
- Bilder (3)
| Artikelname: | XIAP Antibody - middle region |
| Artikelnummer: | ASB-ARP79020_P050 |
| Hersteller Artikelnummer: | ARP79020_P050 |
| Alternativnummer: | ASB-ARP79020_P050-25UL,ASB-ARP79020_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human XIAP |
| Alternative Synonym: | API3, ILP1, MIHA, XLP2, BIRC4, IAP-3, hIAP3, hIAP-3 |
| This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11. |
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Host: Rabbit Target Name: XIAP Sample Tissue: Human Jurkat Whole Cell lysates Antibody Dilution: 1ug/ml |
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Host: Mouse Target Name: XIAP Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml |
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XIAP Antibody - middle region (ARP79020_P050) in Human Jurkat Whole Cell using Western Blot |
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