ABL1 Antibody - middle region
Artikelnummer:
ASB-ARP80033_P050
- Bilder (3)
| Artikelname: | ABL1 Antibody - middle region |
| Artikelnummer: | ASB-ARP80033_P050 |
| Hersteller Artikelnummer: | ARP80033_P050 |
| Alternativnummer: | ASB-ARP80033_P050-25UL,ASB-ARP80033_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human ABL1 |
| Alternative Synonym: | ABL, JTK7, p150, c-ABL, v-abl, CHDSKM, c-ABL1, BCR-ABL, bcr/abl |
| This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9,22) translocation that results in a fusion with the 5 end of the breakpoint cluster region gene (BCR, MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. |
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Rabbit Anti-ABL1 Antibody Catalog Number: ARP80033_P050 Formalin Fixed Paraffin Embedded Tissue: Human Urinary Bladder Tissue Observed Staining: Cytoplasm Primary Antibody Concentration: 1:100 Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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Host: Rabbit Target Name: ABL1 Sample Tissue: Human 293T Whole Cell lysates Antibody Dilution: 1ug/ml |
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ABL1 Antibody - middle region (ARP80033_P050) in Human 293T Whole Cell using Western Blot |
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