PDGFRB Antibody - N-terminal region

Artikelnummer: ASB-ARP80392_P050
Artikelname: PDGFRB Antibody - N-terminal region
Artikelnummer: ASB-ARP80392_P050
Hersteller Artikelnummer: ARP80392_P050
Alternativnummer: ASB-ARP80392_P050-25UL,ASB-ARP80392_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Human
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PDGFRB
Alternative Synonym: IMF1, KOGS, IBGC4, JTK12, PDGFR, PENTT, CD140B, PDGFR1, PDGFR-1
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 121 kDa
NCBI: 5159
UniProt: P09619
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Host: Rabbit
Target Name: PDGFRB
Sample Tissue: Human A549 Whole Cell lysates
Antibody Dilution: 1ug/ml
25 ug of the indicated Human whole cell extracts was loaded onto a 6-18% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Recommended dilution for antibody is 1-3 ug/mL. The n-terminal peptide can also recognize isoform 2 at 37 kDa in some samples.
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