CCNH Antibody - C-terminal region
Artikelnummer:
ASB-AVARP03026_T100
- Bilder (4)
| Artikelname: | CCNH Antibody - C-terminal region |
| Artikelnummer: | ASB-AVARP03026_T100 |
| Hersteller Artikelnummer: | AVARP03026_T100 |
| Alternativnummer: | ASB-AVARP03026_T100-25UL,ASB-AVARP03026_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human CCNH |
| Alternative Synonym: | CAK, p34, p37, CycH |
| Cyclin H regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive carboxyl-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. It is involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. |
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Human Lung |
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WB Suggested Anti-CCNH Antibody Titration: 1ug/ml Positive Control: Jurkat cell lysateCCNH is supported by BioGPS gene expression data to be expressed in Jurkat |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 5 ug/mL of the antibody was used in this experiment. |
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CCNH antibody - C-terminal region (AVARP03026_T100) in Human Jurkat using Western Blot |
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