MYC Antibody - C-terminal region
Artikelnummer:
ASB-AVARP04001_P050
- Bilder (4)
| Artikelname: | MYC Antibody - C-terminal region |
| Artikelnummer: | ASB-AVARP04001_P050 |
| Hersteller Artikelnummer: | AVARP04001_P050 |
| Alternativnummer: | ASB-AVARP04001_P050-25UL,ASB-AVARP04001_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Canine, Human, Mouse, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human MYC |
| Alternative Synonym: | MRTL, MYCC, c-Myc, bHLHe39 |
| MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this MYC gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma.The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitts lymphomas, suggesting its importance in the normal function of this gene. |
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WB Suggested Anti-MYC Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Small Intestine |
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Host: Rabbit Target Name: MYC Sample Tissue: Mouse Heart Antibody Dilution: 1ug/ml |
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Host: Mouse Target Name: MYC Sample Tissue: Mouse Heart Antibody Dilution: 1ug/ml |
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MYC antibody - C-terminal region (AVARP04001_P050) in Human Small Intestine using Western Blot |
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