MAPK14 Antibody - C-terminal region

Artikelnummer: ASB-AVARP06004_T100
Artikelname: MAPK14 Antibody - C-terminal region
Artikelnummer: ASB-AVARP06004_T100
Hersteller Artikelnummer: AVARP06004_T100
Alternativnummer: ASB-AVARP06004_T100-25UL,ASB-AVARP06004_T100-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MAPK14
Alternative Synonym: RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA
MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Klonalität: Polyclonal
Konzentration: 1.0 mg/ml
Molekulargewicht: 41kDa
NCBI: 1432
UniProt: Q16539
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-MAPK14 Antibody
Titration: 0.625 ug/ml
Positive Control: Jurkat Whole CellMAPK14 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
Host: Rabbit
Target Name: MAPK14
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 1ug/ml
MAPK14 antibody - C-terminal region (AVARP06004_T100) in Human Jurkat using Western Blot